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BENIGN PROSTATIC HYPERTROPHY: ETIOLOGY, PATHOGENESIS AND THERAPEUTIC CONSEQUENCES
Prof. Aksam Yassin,
Dept. of Urology & Human Sexuality, Buckhoerner Moor 110, Norderstedt,
Germany.
Due to the higher life and health expectancy in modern
societies, the quality of life (QoL) became a very
important issue in benign prostatic hyperplasia
or syndrome (BPH or BPS)
Population. It is one of the major concepts identified
by patients to be important in relation to sexuality
before and after BPH therapy. Experts expect a drastically
higher increase of elderly population within the
next two decades
We obviously identify - according to the 12 known studies
and to our experience in terms of BPH and sexuality-
a higher correlation between clinically manifested
BPH and erectile/ ejaculatory disorders (ALF ONE
& MSAM-7 studies…). These studies have
more a demographic and statistical characters regarding
to this concern. We were more concerned in our
research group to study the
impact on sexuality in this population not
only as the
result of impaired QoL due to voiding disturbances
or nocturia (tiredness, lack of sleep etc…)
but also to look for the reasons in the Microanatomy
and Histo-chemistry.
The hormonal imbalance (aging related Lack of Testosterone
and DHT) can give a chance for “ Aging
Changes “ in the whole male organism including
the tissues of Prostate and Corpus cavernosum stromas.
The connective collagen stroma will increase, enhancing
the compartments of Alpha-1 Adrenocepros 1 &
2.
Figure
2:
Furthermore the impact on sexuality resulting from the
various treatment modalities of BPH, either medical,
surgical or instrumental has been often neglected
in the past and not sufficiently investigated. We
also try in this presentation to update the influence
on sexual function of current treatments for the
symptomatic BPH.
Professor Aksam Yassin MD PhD
EdD FEBU
Professor of Urology & Human Sexuality
Buckhoerner Moor 110
22846 Norderstedt, Hamburg, Germany
Degrees:
BBMSc. - Bachelor of Basic Medical Sciences, University of Damascus, 1977
MD - Doctor of Medicine, Univ. of Damascus, 1980
FAU - Facharzt fur Urologie (specialist in urology), Hanover, 1986
Ed.D - Doctor of Education, University of Sarasota, Florida/USA, June
1996
Ph.D - Medical Sciences, Hamburg University, September 18th
\ 1998
Clinical Posts:
Consultant Uro-Surgeon, clinic for urology, andrology
and venereal diseases,
Hamburg/Germany,
since 1987 - affiliated
with the urologic academic dept.
At Hamburg
University for BPH and T1/T2 prostate cancer research.
Professor
of Urology, Zurich University/Switzerland,
November 1993
Head of the European Information Office
of the University of Sarasota in
Hamburg/Germany, since 1994
Adjunct Professor, Education and Behavioural Sciences at
the University of
Sarasota, Florida/USA (teaching program for medical sociology and sexual
medicine), since August 1995
Professor
of Urology at the Gulf Medical College Ajman
/ UAE since 2,000.
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