| |
| References
- Vasectomy |
1.
Mullooly JP, Wiest WM, Alexander NJ, Greenlick MR,
Fulgham DL. Vasectomy, serum assays, and
coronary heart disease symptoms and risk factors.
J Clin.Epidemiol. 1993;46:101-109.
Abstract: We compared three serum assays (two
antisperm antibody assays and one assay for circulating
immune complexes) and a number of CHD-related variables
in 69 vasectomized (V) and 126 non-vasectomized (NV)
participants in the Portland Center for the Multiple
Risk Factor Intervention Trial. Significant differences
between the V and NV men were found in sperm agglutination
(SA) and sperm immobilization (SI) titers, as well
as in several CHD risk factors, symptoms, and treatments;
men in the V group had higher titers for SA and SI,
smoked more, and had lower diastolic and systolic
blood pressure than men in the NV group. Differences
between V and NV in SA and SI activity remained even
after we controlled for any effects that CHD risk
factors, symptoms, and treatments may have had on
the serum assays. Antibody development tended to decrease
with age-at-vasectomy and increase with time-post-vasectomy.
In the case of SA the antibodies clearly increased
with time-post-vasectomy.
Notes: Vasectomised patients developed anti-sperm
antibodies which increased with time, especially when
when the operation was performed when young. This
is important when vasectomy is performed in men even
in their twenties. The association with CHD risk factors
is interesting and deserves much more attention than
it has received. One of the authors, Nancy Alexander
has done much good work over twenty years on Vasectomy
and CHD.
|
| back
to reference list - Vasectomy |
| back
to reference library menu |
|
|
The
Andropause Society
- Registered Charity No. 1088008
The
Information on this site is provided for information only,
and is not meant to substitute for the advice of your own
physician or other medical professional. Copyright © 2000
- 2009 The Andropause Society.
|
|
 |